Ontology highlight
ABSTRACT:
SUBMITTER: Gao G
PROVIDER: S-EPMC416542 | biostudies-literature | 2004 Jun
REPOSITORIES: biostudies-literature
Gao Guangping G Vandenberghe Luk H LH Alvira Mauricio R MR Lu You Y Calcedo Roberto R Zhou Xiangyang X Wilson James M JM
Journal of virology 20040601 12
The potential for using Adeno-associated virus (AAV) as a vector for human gene therapy has stimulated interest in the Dependovirus genus. Serologic data suggest that AAV infections are prevalent in humans, although analyses of viruses and viral sequences from clinical samples are extremely limited. Molecular techniques were used in this study to successfully detect endogenous AAV sequences in 18% of all human tissues screened, with the liver and bone marrow being the most predominant sites. Seq ...[more]