Ontology highlight
ABSTRACT:
SUBMITTER: Lu J
PROVIDER: S-EPMC4165441 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Biochemistry 20140902 36
In the F family of conjugative plasmids, TraJ is an essential transcriptional activator of the tra operon that encodes most of the proteins required for conjugation. Here we report for the first time the X-ray crystal structures of the TraJ N-terminal domains from the prototypic F plasmid (TraJF(11-130)) and from the Salmonella virulence plasmid pSLT (TraJpSLT(1-128)). Both structures contain similar Per-ARNT-Sim (PAS) folds, which further homodimerize through the N-terminal helix and the struct ...[more]