Ontology highlight
ABSTRACT:
SUBMITTER: Dix I
PROVIDER: S-EPMC4168697 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Beilstein journal of organic chemistry 20140827
Ethynyl[2.2]paracyclophanes are shown to be useful substrates for the preparation of complex, highly unsaturated carbon frameworks. Thus both the pseudo-geminal- 2 and the pseudo-ortho-diethynylcyclophane 4 can be dimerized by Glaser coupling to the respective dimers 9/10 and 11/12. Whereas the former isomer pair could not be separated so far, the latter provided the pure diastereomers after extensive column chromatography/recrystallization. Isomer 11 is chiral and could be separated on a column ...[more]