Ontology highlight
ABSTRACT:
SUBMITTER: Hong J
PROVIDER: S-EPMC4170621 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Hong Junmou J Liu Zhenguo Z Zhu Hua H Zhang Xin X Liang Yongju Y Yao Shiyuan S Wang Fang F Xie Xiaoyun X Zhang Bo B Tan Tao T Fu Liwu L Nie Jing J Cheng Chao C
Oncotarget 20140701 14
Esophageal quamous cell carcinoma (ESCC) is the predominant histological type of esophageal carcinoma in Asian populations. To date, few biomarkers have been identified for ESCC. In present study, we found a tumor suppressor, NUMB isoform 1 (NUMB-1), as a promising prognostic biomarker for patients with ESCC. NUMB-1 mRNA was downregulated in 66.7% of primary ESCC tissues when compared with matched adjacent non-tumor tissues. The low expression of NUMB-1 was significantly associated with high tum ...[more]