Ontology highlight
ABSTRACT:
SUBMITTER: Bereszczak JZ
PROVIDER: S-EPMC4175414 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Bereszczak Jessica Z JZ Havlik Marlene M Weiss Victor U VU Marchetti-Deschmann Martina M van Duijn Esther E Watts Norman R NR Wingfield Paul T PT Allmaier Guenter G Steven Alasdair C AC Heck Albert J R AJ
Analytical and bioanalytical chemistry 20131220 5
The capsid of hepatitis B virus (HBV) is a major viral antigen and important diagnostic indicator. HBV capsids have prominent protrusions ('spikes') on their surface and are unique in having either T = 3 or T = 4 icosahedral symmetry. Mouse monoclonal and also human polyclonal antibodies bind either near the spike apices (historically the 'α-determinant') or in the 'floor' regions between them (the 'β-determinant'). Native mass spectrometry (MS) and gas-phase electrophoretic mobility molecular a ...[more]