Ontology highlight
ABSTRACT:
SUBMITTER: Saxena M
PROVIDER: S-EPMC4181162 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Saxena Madhukar M Agrawal C G CG Srivastava Neena N Banerjee Monisha M
The Indian journal of medical research 20140701 1
<h4>Background & objectives</h4>Diabetes is a metabolic pro-inflammatory disorder characterized by chronic hyperglycaemia and increased levels of circulating cytokines suggesting a causal role for inflammation in its aetiology. In order to decipher the role of interleukin-6 (IL-6) in type 2 diabetes mellitus (T2DM) we analyzed two promoter polymorphisms -597 A/G (rs1800797) and -174 G/C (rs1800795) in T2DM cases from north India, and in healthy controls.<h4>Methods</h4>DNA was isolated from veno ...[more]