Ontology highlight
ABSTRACT:
SUBMITTER: Wu S
PROVIDER: S-EPMC4182485 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Wu Shuang S Aksoy Munevver M Shi Jianting J Houbaviy Hristo Botev HB
PloS one 20140930 9
Expression of the mouse miR-290-295 cluster and its miR-371-373 homolog in human is restricted to early embryos, primordial germ cells, the germ line stem cell compartment of the adult testis and to stem cell lines derived from the early embryonic lineages. Sequencing data suggest considerable seed diversification between the seven homologous pre-miRNAs of miR-290-295 but it is not clear if all of the implied miR-290-295 seeds are also conserved in the human miR-371-373 cluster, which consists o ...[more]