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Genome of a chronic osteitis-causing Clostridium tetani.


ABSTRACT: We sequenced the genome of a Clostridium tetani strain that caused chronic tibial osteitis without any clinical sign of tetanus in a 26-year-old man previously vaccinated against this disease. The genome contained a plasmid that harboured the tetX-tetR tetanospasmin operon, and was highly similar to that of a tetanus-causing strain.

SUBMITTER: Fournier PE 

PROVIDER: S-EPMC4184619 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature

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Genome of a chronic osteitis-causing Clostridium tetani.

Fournier P-E PE   Levy P-Y PY   Million M M   Croce O O   Blanc-Tailleur C C   Brouqui P P   Raoult D D  

New microbes and new infections 20140128 1


We sequenced the genome of a Clostridium tetani strain that caused chronic tibial osteitis without any clinical sign of tetanus in a 26-year-old man previously vaccinated against this disease. The genome contained a plasmid that harboured the tetX-tetR tetanospasmin operon, and was highly similar to that of a tetanus-causing strain. ...[more]

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