Rapid engineering of versatile molecular logic gates using heterologous genetic transcriptional modules.

ABSTRACT: We designed and constructed versatile modular genetic logic gates in bacterial cells. These function as digital logic 1-input Buffer gate, 2-input and 3-input AND gates with one inverted input and integrate multiple chemical input signals in customised logic manners. Such rapidly engineered devices serve to achieve increased sensing signal selectivity.

SUBMITTER: Wang B 

PROVIDER: S-EPMC4185417 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature