Ontology highlight
ABSTRACT:
SUBMITTER: Keller AN
PROVIDER: S-EPMC4187704 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Keller Andrew N AN Yang Xiao X Wiedermannová Jana J Delumeau Olivier O Krásný Libor L Lewis Peter J PJ
Journal of bacteriology 20140804 20
RNA polymerase in bacteria is a multisubunit protein complex that is essential for gene expression. We have identified a new subunit of RNA polymerase present in the high-A+T Firmicutes phylum of Gram-positive bacteria and have named it ε. Previously ε had been identified as a small protein (ω1) that copurified with RNA polymerase. We have solved the structure of ε by X-ray crystallography and show that it is not an ω subunit. Rather, ε bears remarkable similarity to the Gp2 family of phage prot ...[more]