Ontology highlight
ABSTRACT:
SUBMITTER: Zheng A
PROVIDER: S-EPMC4884477 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Journal of molecular biology 20160402 11
The Sm-protein Hfq facilitates interactions between small non-coding RNA (sRNA) and target mRNAs. In enteric Gram-negative bacteria, Hfq is required for sRNA regulation, and hfq deletion results in stress intolerance and reduced virulence. By contrast, the role of Hfq in Gram-positive is less established and varies among species. The RNA binding and RNA annealing activity of Hfq from Escherichia coli, Pseudomonas aeruginosa, Listeria monocytogenes, Bacillus subtilis, and Staphylococcus aureus we ...[more]