Ontology highlight
ABSTRACT:
SUBMITTER: Amaratunga C
PROVIDER: S-EPMC4187907 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Amaratunga Chanaki C Sreng Sokunthea S Mao Sivanna S Tullo Gregory S GS Anderson Jennifer M JM Chuor Char Meng CM Suon Seila S Fairhurst Rick M RM
Antimicrobial agents and chemotherapy 20140721 10
Chloroquine (CQ) is used to treat Plasmodium vivax malaria in areas where CQ resistance has not been reported. The use of artemisinin (ART)-based combination therapies (ACTs) to treat CQ-sensitive P. vivax infections is effective and convenient but may promote the emergence and worsening of ART resistance in sympatric Plasmodium falciparum populations. Here, we show that CQ effectively treats P. vivax malaria in Pursat Province, western Cambodia, where ART-resistant P. falciparum is highly preva ...[more]