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Polypeptide backbone, C(?) and methyl group resonance assignments of the 24 kDa plectin repeat domain 6 from human protein plectin.


ABSTRACT: The 500 kDa protein plectin is essential for the cytoskeletal organization of most mammalian cells and it is up-regulated in some types of cancer. Here, we report nearly complete sequence-specific polypeptide backbone, (13)C(?) and methyl group resonance assignments for 24 kDa human plectin(4403-4606) containing the C-terminal plectin repeat domain 6.

SUBMITTER: Pulavarti SV 

PROVIDER: S-EPMC4194182 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature

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Polypeptide backbone, C(β) and methyl group resonance assignments of the 24 kDa plectin repeat domain 6 from human protein plectin.

Pulavarti Surya Vsrk SV   Eletsky Alexander A   Huang Yuanpeng J YJ   Acton Thomas B TB   Xiao Rong R   Everett John K JK   Montelione Gaetano T GT   Szyperski Thomas T  

Biomolecular NMR assignments 20140411 1


The 500 kDa protein plectin is essential for the cytoskeletal organization of most mammalian cells and it is up-regulated in some types of cancer. Here, we report nearly complete sequence-specific polypeptide backbone, (13)C(β) and methyl group resonance assignments for 24 kDa human plectin(4403-4606) containing the C-terminal plectin repeat domain 6. ...[more]

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