Ontology highlight
ABSTRACT:
SUBMITTER: Hedges DJ
PROVIDER: S-EPMC419785 | biostudies-literature | 2004 Jun
REPOSITORIES: biostudies-literature
Hedges Dale J DJ Callinan Pauline A PA Cordaux Richard R Xing Jinchuan J Barnes Erin E Batzer Mark A MA
Genome research 20040601 6
Alu elements are primate-specific members of the SINE (short interspersed element) retroposon family, which comprise approximately 10% of the human genome. Here we report the first chromosomal-level comparison examining the Alu retroposition dynamics following the divergence of humans and chimpanzees. We find a twofold increase in Alu insertions in humans in comparison to the common chimpanzee (Pan troglodytes). The genomic diversity (polymorphism for presence or absence of the Alu insertion) as ...[more]