Ontology highlight
ABSTRACT:
SUBMITTER: Ozdemir A
PROVIDER: S-EPMC4201238 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Ozdemir Anil A Ma Lijia L White Kevin P KP Stathopoulos Angelike A
Developmental cell 20141001 1
In Drosophila embryos, a nuclear gradient of the Dorsal (Dl) transcription factor directs differential gene expression along the dorsoventral (DV) axis, translating it into distinct domains that specify future mesodermal, neural, and ectodermal territories. However, the mechanisms used to differentially position gene expression boundaries along this axis are not fully understood. Here, using a combination of approaches, including mutant phenotype analyses and chromatin immunoprecipitation, we sh ...[more]