Ontology highlight
ABSTRACT:
SUBMITTER: Takumi Y
PROVIDER: S-EPMC4203767 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Takumi Yutaka Y Nishio Shin-ya SY Mugridge Kenneth K Oguchi Tomohiro T Hashimoto Shigenari S Suzuki Nobuyoshi N Iwasaki Satoshi S Jolly Claude C Usami Shin-ichi S
PloS one 20141020 10
A cochlear implant is an indispensable apparatus for a profound hearing loss patient. But insertion of the electrode entails a great deal of stress to the cochlea, and may cause irreversible damage to hair cells and related nerve structure. Although damage prevention effects of dexamethasone have been reported, long-term administration is difficult. In this study, we used a dexamethasone-eluting electrode in the guinea pig cochlea, and compared the gene expression after 7 days insertion with tha ...[more]