Ontology highlight
ABSTRACT:
SUBMITTER: Kister I
PROVIDER: S-EPMC4204227 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Neurology(R) neuroimmunology & neuroinflammation 20140918 3
<h4>Objective</h4>To determine the impact of therapeutic infusion of IV immunoglobulin (IVIg) on John Cunningham virus antibody (JCV Ab) serostatus and level in serum.<h4>Methods</h4>We carried out a retrospective analysis of serum levels of JCV Ab among STRATIFY-2 trial enrollees from 2 multiple sclerosis centers who were exposed to IVIg during the trial. For the subset of eligible patients, we estimated mean linear trends while on IVIg and after stopping IVIg with a linear mixed-effects model. ...[more]