Ontology highlight
ABSTRACT:
SUBMITTER: Pu X
PROVIDER: S-EPMC4206576 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Pu X X Wang L L Chang J Y JY Hildebrandt M A T MA Ye Y Y Lu C C Skinner H D HD Niu N N Jenkins G D GD Komaki R R Minna J D JD Roth J A JA Weinshilboum R M RM Wu X X
Clinical pharmacology and therapeutics 20140723 5
Definitive radiotherapy improves locoregional control and survival in inoperable non-small cell lung cancer patients. However, radiation-induced toxicities (pneumonitis/esophagitis) are common dose-limiting inflammatory conditions. We therefore conducted a pathway-based analysis to identify inflammation-related single-nucleotide polymorphisms associated with radiation-induced pneumonitis or esophagitis. A total of 11,930 single-nucleotide polymorphisms were genotyped in 201 stage I-III non-small ...[more]