A role for A-to-I RNA editing in temperature adaptation.
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ABSTRACT:
SUBMITTER: Garrett SC
PROVIDER: S-EPMC4208822 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Publications
A role for A-to-I RNA editing in temperature adaptation.
Garrett Sandra C SC Rosenthal Joshua J C JJ
Physiology (Bethesda, Md.) 20121201 6
A-to-I RNA editing can recode mRNAs, giving organisms the option to express diverse, functionally distinct protein isoforms. Here, we propose that RNA editing is inherently geared for temperature adaptation because it tends to recode to smaller, less stabilizing amino acids. Studies on how editing affects protein function support this idea. ...[more]
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