Ontology highlight
ABSTRACT:
SUBMITTER: Cardinal P
PROVIDER: S-EPMC4209357 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Cardinal Pierre P André Caroline C Quarta Carmelo C Bellocchio Luigi L Clark Samantha S Elie Melissa M Leste-Lasserre Thierry T Maitre Marlene M Gonzales Delphine D Cannich Astrid A Pagotto Uberto U Marsicano Giovanni G Cota Daniela D
Molecular metabolism 20140801 7
Metabolic flexibility allows rapid adaptation to dietary change, however, little is known about the CNS mechanisms regulating this process. Neurons in the hypothalamic ventromedial nucleus (VMN) participate in energy balance and are the target of the metabolically relevant hormone leptin. Cannabinoid type-1 (CB1) receptors are expressed in VMN neurons, but the specific contribution of endocannabinoid signaling in this neuronal population to energy balance regulation is unknown. Here we demonstra ...[more]