Ontology highlight
ABSTRACT:
SUBMITTER: Hummel R
PROVIDER: S-EPMC4209553 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Hummel Richard R Sie Corina C Watson David I DI Wang Tingting T Ansar Alfiya A Michael Michael Z MZ Van der Hoek Mark M Haier Joerg J Hussey Damian J DJ
World journal of gastroenterology 20141001 40
<h4>Aim</h4>To investigate expression of microRNA (miRNA) and potential targets in chemotherapy resistant esophageal cancer cell lines.<h4>Methods</h4>An in-vitro model of acquired chemotherapy resistance in esophageal adeno- (EAC) and squamous cell carcinoma (ESCC) cells was used, and microRNA expression profiles for cisplatin or 5-fluorouracil (5-FU) resistant variants vs chemotherapy sensitive controls were compared using microarray and quantitative real-time polymerase chain reaction (PCR). ...[more]