Ontology highlight
ABSTRACT:
SUBMITTER: Rhee M
PROVIDER: S-EPMC4213212 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Rhee Minsoung M Light Yooli K YK Yilmaz Suzan S Adams Paul D PD Saxena Deepak D Meagher Robert J RJ Singh Anup K AK
Lab on a chip 20141001 23
Picoinjection is a promising technique to add reagents into pre-formed emulsion droplets on chip however, it is sensitive to pressure fluctuation, making stable operation of the picoinjector challenging. We present a chip architecture using a simple pressure stabilizer for consistent and highly reproducible picoinjection in multi-step biochemical assays with droplets. Incorporation of the stabilizer immediately upstream of a picoinjector or a combination of injectors greatly reduces pressure flu ...[more]