Porcine SLITRK1: Molecular cloning and characterization.
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ABSTRACT:
SUBMITTER: Larsen K
PROVIDER: S-EPMC4215120 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Porcine SLITRK1: Molecular cloning and characterization.
Larsen Knud K Momeni Jamal J Farajzadeh Leila L Bendixen Christian C
FEBS open bio 20141007
The membrane protein SLITRK1 functions as a developmentally regulated stimulator of neurite outgrowth and variants in this gene have been implicated in Tourette syndrome. In the current study we have cloned and characterized the porcine SLITRK1 gene. The genomic organization of SLITRK1 lacks introns, as does its human and mouse counterparts. RT-PCR cloning revealed two SLITRK1 transcripts: a full-length mRNA and a transcript variant that results in a truncated protein. The encoded SLITRK1 protei ...[more]
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