Ontology highlight
ABSTRACT:
SUBMITTER: De Rossi G
PROVIDER: S-EPMC4215719 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Journal of cell science 20141101 Pt 21
Angiogenesis is essential for the development of a normal vasculature, tissue repair and reproduction, and also has roles in the progression of diseases such as cancer and rheumatoid arthritis. The heparan sulphate proteoglycan syndecan-2 is expressed on mesenchymal cells in the vasculature and, like the other members of its family, can be shed from the cell surface resulting in the release of its extracellular core protein. The purpose of this study was to establish whether shed syndecan-2 affe ...[more]