Dataset Information

National Cancer Institute's Cancer Disparities Research Partnership Program: Experience and Lessons Learned.

ABSTRACT:

Purpose

To increase access of underserved/health disparities communities to National Cancer Institute (NCI) clinical trials, the Radiation Research Program piloted a unique model - the Cancer Disparities Research Partnership (CDRP) program. CDRP targeted community hospitals with a limited past NCI funding history and provided funding to establish the infrastructure for their clinical research program.

Methods

Initially, 5-year planning phase funding was awarded to six CDRP institutions through a cooperative agreement (U56). Five were subsequently eligible to compete for 5-year implementation phase (U54) funding and three received a second award. Additionally, the NCI Center to Reduce Cancer Health Disparities supported their U56 patient navigation programs.

Results

Community-based hospitals with little or no clinical trials experience required at least a year to develop the infrastructure and establish community outreach/education and patient navigation programs before accrual to clinical trials could begin. Once established, CDRP sites increased their yearly patient accrual mainly to NCI-sponsored cooperative group trials (~60%) and Principal Investigator/mentor-initiated trials (~30%). The total number of patients accrued on all types of trials was 2,371, while 5,147 patients received navigation services.

Conclusion

Despite a historical gap in participation in clinical cancer research, underserved communities are willing/eager to participate. Since a limited number of cooperative group trials address locally advanced diseases seen in health disparities populations; this shortcoming needs to be rectified. Sustainability for these programs remains a challenge. Addressing these gaps through research and public health mechanisms may have an important impact on their health, scientific progress, and efforts to increase diversity in NCI clinical trials.

SUBMITTER: Wong RS

PROVIDER: S-EPMC4217306 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature

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Publications

National Cancer Institute's Cancer Disparities Research Partnership Program: Experience and Lessons Learned.

Wong Rosemary S L RS Vikram Bhadrasain B Govern Frank S FS Petereit Daniel G DG Maguire Patrick D PD Clarkson Maggie R MR Heron Dwight E DE Coleman C Norman CN

Frontiers in oncology 20141103

<h4>Purpose</h4>To increase access of underserved/health disparities communities to National Cancer Institute (NCI) clinical trials, the Radiation Research Program piloted a unique model - the Cancer Disparities Research Partnership (CDRP) program. CDRP targeted community hospitals with a limited past NCI funding history and provided funding to establish the infrastructure for their clinical research program.<h4>Methods</h4>Initially, 5-year planning phase funding was awarded to six CDRP institu ...[more]

PMID: 25405101

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Dataset Information

National Cancer Institute's Cancer Disparities Research Partnership Program: Experience and Lessons Learned.

Purpose

Methods

Results

Conclusion

Publications

National Cancer Institute's Cancer Disparities Research Partnership Program: Experience and Lessons Learned.

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