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Diuretic exposure in premature infants from 1997 to 2011.


ABSTRACT: OBJECTIVE:Diuretics are often prescribed off-label to premature infants, particularly to prevent or treat bronchopulmonary dysplasia. We examined their use and safety in this group. STUDY DESIGN:Retrospective cohort study of infants?

SUBMITTER: Laughon MM 

PROVIDER: S-EPMC4223004 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature

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Diuretic exposure in premature infants from 1997 to 2011.

Laughon Matthew M MM   Chantala Kim K   Aliaga Sofia S   Herring Amy H AH   Hornik Christoph P CP   Hughes Rachel R   Clark Reese H RH   Smith P Brian PB  

American journal of perinatology 20140506 1


<h4>Objective</h4>Diuretics are often prescribed off-label to premature infants, particularly to prevent or treat bronchopulmonary dysplasia. We examined their use and safety in this group.<h4>Study design</h4>Retrospective cohort study of infants < 32 weeks gestation and < 1,500 g birth weight exposed to diuretics in 333 neonatal intensive care units from 1997 to 2011. We examined use of acetazolamide, amiloride, bumetanide, chlorothiazide, diazoxide, ethacrynic acid, furosemide, hydrochlorothi  ...[more]

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