Ontology highlight
ABSTRACT:
SUBMITTER: Lakin MR
PROVIDER: S-EPMC4223911 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Lakin Matthew R MR Minnich Amanda A Lane Terran T Stefanovic Darko D
Journal of the Royal Society, Interface 20141201 101
Learning and adaptive behaviour are fundamental biological processes. A key goal in the field of bioengineering is to develop biochemical circuit architectures with the ability to adapt to dynamic chemical environments. Here, we present a novel design for a biomolecular circuit capable of supervised learning of linear functions, using a model based on chemical reactions catalysed by DNAzymes. To achieve this, we propose a novel mechanism of maintaining and modifying internal state in biochemical ...[more]