Ontology highlight
ABSTRACT:
SUBMITTER: Brophy JA
PROVIDER: S-EPMC4230274 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Nature methods 20140501 5
Cells navigate environments, communicate and build complex patterns by initiating gene expression in response to specific signals. Engineers seek to harness this capability to program cells to perform tasks or create chemicals and materials that match the complexity seen in nature. This Review describes new tools that aid the construction of genetic circuits. Circuit dynamics can be influenced by the choice of regulators and changed with expression 'tuning knobs'. We collate the failure modes en ...[more]