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A universal isocyanide for diverse heterocycle syntheses.


ABSTRACT: Novel scaffolds are of uttermost importance for the discovery of functional material. Three different heterocyclic scaffolds easily accessible from isocyanoacetaldehyde dimethylacetal 1 by multicomponent reaction (MCR) are described. They can be efficiently synthesized by a Ugi tetrazole multicomponent reaction of 1. We discuss the synthesis, 3D structures, and other physicochemical properties.

SUBMITTER: Patil P 

PROVIDER: S-EPMC4227542 | biostudies-literature |

REPOSITORIES: biostudies-literature

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