Ontology highlight
ABSTRACT:
SUBMITTER: Al-Henhena N
PROVIDER: S-EPMC4229078 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Al-Henhena Nawal N Ying Rozaida Poh Yuen RP Ismail Salmah S Najm Walaa W Khalifa Shaden A M SA El-Seedi Hesham H Ameen Abdulla Mahmood M
PloS one 20141112 11
Andrographis paniculata is a grass-shaped medicinal herb, traditionally used in Southeast Asia. The aim of this study was to evaluate the chemoprotective effects of A. paniculata on colorectal cancer. A. paniculata ethanol extract was tested on azoxymethane (AOM)-induced aberrant crypt foci (ACF) in vivo and in vitro. A. paniculata treated groups showed a significant reduction in the number of ACF of the treated rats. Microscopically, ACF showed remarkably elongated and stratified cells, and dep ...[more]