Ontology highlight
ABSTRACT:
SUBMITTER: Bery A
PROVIDER: S-EPMC4230032 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Bery Anand A Leung Felix F Smith Christopher R CR Diamandis Eleftherios P EP Kulasingam Vathany V
Clinical proteomics 20140402 1
<h4>Background</h4>Conventional proteomic approaches have thus far been unable to identify novel serum biomarkers for ovarian cancer that are more sensitive and specific than the current clinically used marker, CA-125. Because endogenous peptides are smaller and may enter the circulation more easily than proteins, a focus on the low-molecular-weight region may reveal novel biomarkers with enhanced sensitivity and specificity. In this study, we deciphered the peptidome of ascites fluid from 3 ova ...[more]