Ontology highlight
ABSTRACT:
SUBMITTER: Wetherill L
PROVIDER: S-EPMC4233207 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Wetherill Leah L Agrawal Arpana A Kapoor Manav M Bertelsen Sarah S Bierut Laura J LJ Brooks Andrew A Dick Danielle D Hesselbrock Michie M Hesselbrock Victor V Koller Daniel L DL Le Nhung N Nurnberger John I JI Salvatore Jessica E JE Schuckit Marc M Tischfield Jay A JA Wang Jen-Chyong JC Xuei Xiaoling X Edenberg Howard J HJ Porjesz Bernice B Bucholz Kathleen K Goate Alison M AM Foroud Tatiana T
Addiction biology 20140516 3
Alcohol and drug use disorders are individually heritable (50%). Twin studies indicate that alcohol and substance use disorders share common genetic influences, and therefore may represent a more heritable form of addiction and thus be more powerful for genetic studies. This study utilized data from 2322 subjects from 118 European-American families in the Collaborative Study on the Genetics of Alcoholism sample to conduct genome-wide association analysis of a binary and a continuous index of gen ...[more]