Ontology highlight
ABSTRACT:
SUBMITTER: Jindani A
PROVIDER: S-EPMC4233406 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Jindani Amina A Harrison Thomas S TS Nunn Andrew J AJ Phillips Patrick P J PP Churchyard Gavin J GJ Charalambous Salome S Hatherill Mark M Geldenhuys Hennie H McIlleron Helen M HM Zvada Simbarashe P SP Mungofa Stanley S Shah Nasir A NA Zizhou Simukai S Magweta Lloyd L Shepherd James J Nyirenda Sambayawo S van Dijk Janneke H JH Clouting Heather E HE Coleman David D Bateson Anna L E AL McHugh Timothy D TD Butcher Philip D PD Mitchison Denny A DA
The New England journal of medicine 20141001 17
<h4>Background</h4>Tuberculosis regimens that are shorter and simpler than the current 6-month daily regimen are needed.<h4>Methods</h4>We randomly assigned patients with newly diagnosed, smear-positive, drug-sensitive tuberculosis to one of three regimens: a control regimen that included 2 months of ethambutol, isoniazid, rifampicin, and pyrazinamide administered daily followed by 4 months of daily isoniazid and rifampicin; a 4-month regimen in which the isoniazid in the control regimen was rep ...[more]