Stem cell-based therapies for cancer treatment: separating hope from hype.
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ABSTRACT:
SUBMITTER: Stuckey DW
PROVIDER: S-EPMC4234304 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Publications
Stem cell-based therapies for cancer treatment: separating hope from hype.
Stuckey Daniel W DW Shah Khalid K
Nature reviews. Cancer 20140901 10
Stem cell-based therapies are emerging as a promising strategy to tackle cancer. Multiple stem cell types have been shown to exhibit inherent tropism towards tumours. Moreover, when engineered to express therapeutic agents, these pathotropic delivery vehicles can effectively target sites of malignancy. This perspective considers the current status of stem cell-based treatments for cancer and provides a rationale for translating the most promising preclinical studies into the clinic. ...[more]
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