Ontology highlight
ABSTRACT:
SUBMITTER: Warimwe GM
PROVIDER: S-EPMC4235025 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Warimwe George M GM Lorenzo Gema G Lopez-Gil Elena E Reyes-Sandoval Arturo A Cottingham Matthew G MG Spencer Alexandra J AJ Collins Katharine A KA Dicks Matthew D J MD Milicic Anita A Lall Amar A Furze Julie J Turner Alison V AV Hill Adrian V S AV Brun Alejandro A Gilbert Sarah C SC
Virology journal 20131205
<h4>Background</h4>Rift Valley Fever (RVF) is a viral zoonosis that historically affects livestock production and human health in sub-Saharan Africa, though epizootics have also occurred in the Arabian Peninsula. Whilst an effective live-attenuated vaccine is available for livestock, there is currently no licensed human RVF vaccine. Replication-deficient chimpanzee adenovirus (ChAd) vectors are an ideal platform for development of a human RVF vaccine, given the low prevalence of neutralizing ant ...[more]