Ontology highlight
ABSTRACT:
SUBMITTER: Mukherjee C
PROVIDER: S-EPMC4235972 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Mukherjee Chinmoy C Liu Lin L Pohl Nicola L B NL
Advanced synthesis & catalysis 20140701 10
The combination of benzyl bromide, sodium hydroxide and 15-crown-5 in tetrahydrofuran is shown to be an efficient method for installing benzyl groups at both the 4- and 6-positions regioselectively directly from peracetylated <i>N</i>-trichloroacetyl-protected glucosamine and galactosamine. Application of this benzylation strategy proved to significantly shorten the synthetic route to hyaluronic acid tetra- and hexamers. ...[more]