Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells.
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ABSTRACT:
SUBMITTER: Zhang M
PROVIDER: S-EPMC4236216 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Cytotoxicity induced by nanobacteria and nanohydroxyapatites in human choriocarcinoma cells.
Zhang Mingjun M Yang Jinmei J Shu Jing J Fu Changhong C Liu Shengnan S Xu Ge G Zhang Dechun D
Nanoscale research letters 20141114 1
We explored the cytotoxic effects of nanobacteria (NB) and nanohydroxyapatites (nHAPs) against human choriocarcinoma cells (JAR) and the mechanisms of action underlying their cytotoxicity. JAR cells were co-cultured with NB and nHAPs for 48 h, and ultrastructural changes were more readily induced by NB than nHAPs. Autophagy in the plasma of JAR cells were observed in the NB group. The rate of apoptosis induced by NB was higher than that for nHAPs. The expression of Bax and FasR proteins in the N ...[more]
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