Decreased effective connectivity from cortices to the right parahippocampal gyrus in Alzheimer's disease subjects.
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ABSTRACT:
SUBMITTER: Chen G
PROVIDER: S-EPMC4238239 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Publications
Decreased effective connectivity from cortices to the right parahippocampal gyrus in Alzheimer's disease subjects.
Chen Guangyu G Ward B Douglas BD Chen Gang G Li Shi-Jiang SJ
Brain connectivity 20141101 9
The purpose of this study was to detect effective connectivity (EC) changes in the default mode network and hippocampus network in 20 patients with Alzheimer's disease (AD) and 20 cognitively normal (CN) subjects, using multivariate Granger causality. The authors used the maximum coefficients in the multivariate autoregression model to quantitatively measure the different EC strength levels between the CN and AD groups. It was demonstrated that the EC strength difference can classify AD from CN ...[more]
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