Ontology highlight
ABSTRACT:
SUBMITTER: Hong JY
PROVIDER: S-EPMC4239606 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Hong Jin Young JY Lee Sung Ho SH Lee Seung Chan SC Kim Jong-Wan JW Kim Kee-Pyo KP Kim Sung Min SM Tapia Natalia N Lim Kyung Tae KT Kim Jonghun J Ahn Hong-Sun HS Ko Kinarm K Shin Chan Young CY Lee Hoon Taek HT Schöler Hans R HR Hyun Jung Keun JK Han Dong Wook DW
The Journal of biological chemistry 20141006 47
The spinal cord does not spontaneously regenerate, and treatment that ensures functional recovery after spinal cord injury (SCI) is still not available. Recently, fibroblasts have been directly converted into induced neural stem cells (iNSCs) by the forced expression defined transcription factors. Although directly converted iNSCs have been considered to be a cell source for clinical applications, their therapeutic potential has not yet been investigated. Here we show that iNSCs directly convert ...[more]