Ontology highlight
ABSTRACT:
SUBMITTER: Miyazaki Y
PROVIDER: S-EPMC4240710 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Miyazaki Yasunari Y Vieira-de-Abreu Adriana A Harris Estelle S ES Shah Amrapali M AM Weyrich Andrew S AS Castro-Faria-Neto Hugo C HC Zimmerman Guy A GA
PloS one 20141121 11
Integrin α(D)β(2) is the most recently identified member of the leukocyte, or β(2), subfamily of integrin heterodimers. Its distribution and functions on human leukocytes have not been clearly defined and are controversial. We examined these issues and found that α(D)β(2) is prominently expressed by leukocytes in whole blood from healthy human subjects, including most polymorphonuclear leukocytes and monocytes. We also found that α(D)β(2) is displayed by leukocytes in the alveoli of uninjured an ...[more]