Ontology highlight
ABSTRACT:
SUBMITTER: Radzimanowski J
PROVIDER: S-EPMC4241103 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Protein science : a publication of the Protein Society 20140904 11
Filoviruses are the causative agents of a severe and often fatal hemorrhagic fever with repeated outbreaks in Africa. They are negative sense single stranded enveloped viruses that can cross species barriers from its natural host bats to primates including humans. The small size of the genome poses limits to viral adaption, which may be partially overcome by conformational plasticity. Here we review the different conformational states of the Ebola virus (EBOV) matrix protein VP40 that range from ...[more]