Ontology highlight
ABSTRACT:
SUBMITTER: Bandaru S
PROVIDER: S-EPMC4248348 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Bandaru Srinivas S Marri Vijaya Kumar VK Kasera Priyadarshani P Kovuri Purnima P Girdhar Amandeep A Mittal Deepti Raj DR Ikram Sabeen S Gv Ravi R Nayarisseri Anuraj A
Bioinformation 20141030 10
Montelukast and Zafirlukast are known leukotriene receptor antagonists prescribed in asthma treatment. However, these fall short as mono therapy and are frequently used in combination with inhaled glucocorticosteroids with or without long acting beta 2 agonists. Therefore, it is of interest to apply ligand and structure based virtual screening strategies to identify compounds akin to lead compounds Montelukast and Zafirlukast. Hence, compounds with structures having 95% similarity to these compo ...[more]