Mannose metabolism: more than meets the eye.
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ABSTRACT:
SUBMITTER: Sharma V
PROVIDER: S-EPMC4252654 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Publications
Mannose metabolism: more than meets the eye.
Sharma Vandana V Ichikawa Mie M Freeze Hudson H HH
Biochemical and biophysical research communications 20140612 2
Mannose is a simple sugar with a complex life. It is a welcome therapy for genetic and acquired human diseases, but it kills honeybees and blinds baby mice. It could cause diabetic complications. Mannose chemistry, metabolism, and metabolomics in cells, tissues and mammals can help explain these multiple systemic effects. Mannose has good, bad or ugly outcomes depending on its steady state levels and metabolic flux. This review describes the role of mannose at cellular level and its impact on or ...[more]
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