Ontology highlight
ABSTRACT:
SUBMITTER: Tamaoki N
PROVIDER: S-EPMC4255186 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Tamaoki Naritaka N Takahashi Kazutoshi K Aoki Hitomi H Iida Kazuki K Kawaguchi Tomoko T Hatakeyama Daijirou D Inden Masatoshi M Chosa Naoyuki N Ishisaki Akira A Kunisada Takahiro T Shibata Toshiyuki T Goshima Naoki N Yamanaka Shinya S Tezuka Ken-ichi K
Scientific reports 20141204
The reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) by defined transcription factors has been a well-established technique and will provide an invaluable resource for regenerative medicine. However, the low reprogramming efficiency of human iPSC is still a limitation for clinical application. Here we showed that the reprogramming potential of human dental pulp cells (DPCs) obtained from immature teeth is much higher than those of mature teeth DPCs. Furthermore, immatur ...[more]