Ontology highlight
ABSTRACT:
SUBMITTER: Nolting JF
PROVIDER: S-EPMC4255224 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Nolting Jens-Friedrich JF Möbius Wiebke W Köster Sarah S
Biophysical journal 20141202 11
Along with microtubules and microfilaments, intermediate filaments are a major component of the eukaryotic cytoskeleton and play a key role in cell mechanics. In cells, keratin intermediate filaments form networks of bundles that are sparser in structure and have lower connectivity than, for example, actin networks. Because of this, bending and buckling play an important role in these networks. Buckling events, which occur due to compressive intracellular forces and cross-talk between the kerati ...[more]