Ontology highlight
ABSTRACT:
SUBMITTER: Jiang N
PROVIDER: S-EPMC4255770 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Jiang Ning N Wang Lin L Chen Jing J Wang Luwen L Leach Lindsey L Luo Zewei Z
Genome biology and evolution 20141028 11
DNA methylation in the genome plays a fundamental role in the regulation of gene expression and is widespread in the genome of eukaryotic species. For example, in higher vertebrates, there is a "global" methylation pattern involving complete methylation of CpG sites genome-wide, except in promoter regions that are typically enriched for CpG dinucleotides, or so called "CpG islands." Here, we comprehensively examined and compared the distribution of CpG sites within ten model eukaryotic species a ...[more]