Computational analysis of three-dimensional epithelial morphogenesis using vertex models.
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ABSTRACT:
SUBMITTER: Du X
PROVIDER: S-EPMC4256082 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
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Computational analysis of three-dimensional epithelial morphogenesis using vertex models.
Du XinXin X Osterfield Miriam M Shvartsman Stanislav Y SY
Physical biology 20141120 6
The folding of epithelial sheets, accompanied by cell shape changes and rearrangements, gives rise to three-dimensional structures during development. Recently, some aspects of epithelial morphogenesis have been modeled using vertex models, in which each cell is approximated by a polygon; however, these models have been largely confined to two dimensions. Here, we describe an adaptation of these models in which the classical two-dimensional vertex model is embedded in three dimensions. This modi ...[more]
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