Ontology highlight
ABSTRACT:
SUBMITTER: Gueguen E
PROVIDER: S-EPMC4256274 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Gueguen Erwan E Wills Norma M NM Atkins John F JF Cascales Eric E
PLoS genetics 20141204 12
The Type VI secretion system (T6SS) mediates toxin delivery into both eukaryotic and prokaryotic cells. It is composed of a cytoplasmic structure resembling the tail of contractile bacteriophages anchored to the cell envelope through a membrane complex composed of the TssL and TssM inner membrane proteins and of the TssJ outer membrane lipoprotein. The C-terminal domain of TssM is required for its interaction with TssJ, and for the function of the T6SS. In Citrobacter rodentium, the tssM1 gene d ...[more]