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Crystal structure of 1-(2-chloro-acet-yl)-2,6-bis-(4-fluoro-phen-yl)-3,3-di-methyl-piperidin-4-one.

ABSTRACT: In the title mol-ecule, C21H20ClF2NO2, the piperidine ring adopts a slightly distorted boat conformation. The two benzene rings form a dihedral angle of 87.43?(1)°. A weak intra-molecular C-H?? inter-action is observed. In the crystal, weak C-H?O hydrogen bonds and weak C-H?? inter-actions connect the mol-ecules, forming a three-dimensional network.

SUBMITTER: Jothivel S

PROVIDER: S-EPMC4257194 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature

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Crystal structure of 1-(2-chloro-acet-yl)-2,6-bis-(4-fluoro-phen-yl)-3,3-di-methyl-piperidin-4-one.

Jothivel S S Kotoky Jibon J Kabilan S S

Acta crystallographica. Section E, Structure reports online 20140930 Pt 10

In the title mol-ecule, C21H20ClF2NO2, the piperidine ring adopts a slightly distorted boat conformation. The two benzene rings form a dihedral angle of 87.43 (1)°. A weak intra-molecular C-H⋯π inter-action is observed. In the crystal, weak C-H⋯O hydrogen bonds and weak C-H⋯π inter-actions connect the mol-ecules, forming a three-dimensional network. ...[more]

PMID: 25484669

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