Genetic determinants in the development of sensitization to environmental allergens in early childhood.
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ABSTRACT:
SUBMITTER: Tripathi P
PROVIDER: S-EPMC4257764 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Publications
Genetic determinants in the development of sensitization to environmental allergens in early childhood.
Tripathi Priya P Hong Xiumei X Caruso Deanna D Gao Peisong P Wang Xiaobin X
Immunity, inflammation and disease 20141120 3
Sensitization to environmental allergens remains one of the strongest risk factors for asthma, and there is likely a genetic basis. We sought to identify genetic determinants for the development of allergic sensitization to environmental allergens, particularly cockroach allergen, in early childhood. A total of 631 children with the information about genotypic data on 895 single nucleotide polymorphisms (SNPs) in 179 candidate genes were selected from an existing dataset (Boston Birth Cohort). G ...[more]
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